Votrient™ (
pazopanib) is a prescription medication approved for the treatment of advanced renal cell carcinoma (
kidney cancer). It belongs to a group of medicines called
tyrosine kinase inhibitors.
Who Makes This Medication?
Votrient is made by GlaxoSmithKline.
Votrient works by blocking an enzyme in the body known as tyrosine kinase. This enzyme tells cancer cells to grow and divide. By blocking tyrosine kinase, Votrient may slow down the growth of cancer cells.
Clinical Effects of Votrient
In a clinical study, Votrient improved "progression-free survival" (PFS), which is the period of time the cancer does not get worse. In this study, people with advanced kidney cancer who took Votrient had an average of 9.2 months of PFS, compared with 4.2 months in people taking a placebo (a "sugar pill" that does not contain any active ingredients).
Some general considerations to keep in mind during treatment with Votrient include the following:
- This medication comes in the form of a tablet. It is taken by mouth once a day.
- You should take Votrient on an empty stomach, one hour before or two hours after a meal.
- Votrient should be swallowed whole. Do not crush, chew, or cut the tablets.
- Avoid drinking grapefruit juice while taking this medication.
- Try to take your dose at the same time each day to keep an even level of the drug in your bloodstream. It will also help you remember to take your dose.
- For the medication to work properly, it must be taken as prescribed.
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