Votrient Warnings and Precautions

If you take Votrient, you may have an increased risk for liver problems, heart attacks, strokes, or various other complications. This medicine can also cause interactions when it is combined with certain products. Other safety warnings and precautions with Votrient include potential risks for women who are pregnant or breastfeeding and the possibility of complications in people with certain allergies.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Votrient® (pazopanib) if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • High blood pressure (hypertension)
  • An irregular heartbeat or a heart condition known as QT prolongation
  • Heart disease
  • A history of a heart attack or chest pain
  • A history of stroke or transient ischemic attack (TIA or mini-stroke)
  • Had bleeding in your stomach, intestines, or brain, or you have coughed up blood in the past six months
  • An underactive thyroid (hypothyroidism)
  • Had surgery in the past seven days or have an upcoming surgery
  • A tear in your stomach or intestines (a perforation) or an abnormal connection between two parts of your gastrointestinal tract (a fistula)
  • Been told you have abnormal amounts of protein in your urine
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
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Votrient Medication Information

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