Torisel Drug Interactions

P-Glycoprotein (Pgp) Inducers
P-glycoprotein is a natural protein that helps remove substances, such as medications, from the tissues in the body, so they can be excreted through the urine or feces. Pgp helps remove Torisel from the body. Certain other medications known as Pgp inducers increase the activity of Pgp.
 
When combined with a Pgp inducer, Torisel may be removed from the body too quickly, potentially making it less effective. Your healthcare provider may choose to monitor you more closely if you combine Torisel with a Pgp inducer, and adjust your dose as needed.
 
P-Glycoprotein (Pgp) Inhibitors
P-glycoprotein is a natural protein that helps remove substances, such as medications, from the tissues in the body, so they can be excreted through the urine or feces. Pgp helps remove Torisel from the body. Certain other medications known as Pgp inhibitors decrease the activity of Pgp.
 
When combined with a Pgp inhibitor, Torisel may be removed from the body more slowly, potentially increasing Torisel blood levels and the risk for side effects. Your healthcare provider may choose to monitor you more closely if you combine Torisel with a Pgp inhibitor, and lower your dose if needed.
 
Pimecrolimus
It is recommended that people receiving Torisel not use pimecrolimus because of an increased risk for infection, lymphoma (cancer of the lymph nodes), and skin cancer. Talk to your healthcare provider before taking these medicines together.
 
Sipuleucel-T
Torisel can make sipuleucel-T less effective. Talk to your healthcare provider before combining these medicines.
 
Sunitinib
Torisel may increase the risk for side effects from sunitinib. It is generally recommended that these medicines not be used together. If your healthcare provider recommends you combine Torisel with sunitinib, he or she may need to monitor you more closely.
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Torisel Medication Information

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