Torisel and Breastfeeding

The manufacturer of Torisel (temsirolimus) recommends that nursing women not use this drug, as it is unknown whether the medicine passes through human breast milk or if it would harm a nursing infant. Due to the potential risks to a nursing infant, women should not use Torisel while breastfeeding without first talking to their doctor.

Can Breastfeeding Women Receive Torisel?

Torisel® (temsirolimus) is a prescription medication used in the treatment of advanced renal cell carcinoma (cancer that started in the kidney). At this time, it is unknown whether Torisel passes through breast milk in humans. The manufacturer of the medication recommends women not use Torisel while breastfeeding.
 

More Information About Torisel and Breastfeeding

There is limited information available on the use of this drug during breastfeeding. This drug has not been studied in women who are breastfeeding, so it is unknown if Torisel passes through breast milk, or would harm a nursing infant.
 
Torisel is broken down by the body into a medication known as sirolimus (Rapamune®). Sirolimus has been shown to pass through the breast milk of rats in small amounts. Based on the properties of Torisel and sirolimus, they are expected to also pass through human breast milk to some extent.
 
Because Torisel is associated with potentially serious side effects, and because there is such little information available on the use of the medication in breastfeeding women, a different medication may be preferred in women who choose to breastfeed. If your healthcare provider recommends Torisel while breastfeeding, be watchful for any possible Torisel side effects in your child, and contact your child's healthcare provider if you observe any problems.
 

Talking With Your Healthcare Provider

You should discuss breastfeeding and Torisel use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
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Torisel Medication Information

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