Simulect and Breastfeeding

It is not known whether Simulect (basiliximab) passes through human breast milk. This medicine is a manufactured version of a naturally occurring antibody, which is known to pass through breast milk. Therefore, it is likely that Simulect would pass through breast milk. Due to the potentially serious side effects associated with this drug, breastfeeding women should talk to their healthcare provider before using Simulect.

Can Breastfeeding Women Receive Simulect?

Simulect® (basiliximab) is a prescription medication approved to help prevent kidney transplant rejection in adults and children. It is given as two doses -- one the day of the transplant surgery and another four days later.
At this time, it is unknown if Simulect passes through breast milk. The manufacturer of the medication recommends that women not use it while breastfeeding.

More Information on Simulect and Breastfeeding

At this time, Simulect has not been studied in breastfeeding women. Therefore, it is not known for certain whether the medicine passes through breast milk, or whether it would harm a nursing child.
Simulect is a manufactured form of immunoglobulin G (IgG), an antibody made by the immune system. Because natural IgG is known to pass through breast milk, it is likely that Simulect would also pass through breast milk to some extent.
Normally, very little IgG is absorbed from a nursing infant's digestive tract into the infant's bloodstream. However, because Simulect has not been studied in nursing women, it is unknown how much (if any) medicine a nursing child would be exposed to. Because Simulect is associated with potentially serious side effects, such as infections, it may be best to avoid breastfeeding while receiving the medicine.
If your healthcare provider recommends breastfeeding during Simulect treatment, make sure to let your child's healthcare provider know if you notice any possible Simulect side effects in your child. Side effects may include but are not limited to:
  • Changes in bowel habits
  • Vomiting
  • Difficulty feeding
  • Problems sleeping
  • Gassiness
  • Fever
  • Coughing
  • Excessive crying
  • Abnormal bruising or bleeding
  • Runny nose.
Baby Milestones You've Never Heard Of

Simulect Medication Information

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