What Is the Mechanism of Action for Prograf?

Available by prescription only, Prograf® (tacrolimus) is an immunosuppressant used to prevent organ rejection in people who have had a heart, liver, or kidney transplant.
 
Prograf works by suppressing the immune system, making it less active. The body's natural response to a foreign material, such as a newly transplanted organ, is to attack it. Because Prograf makes the immune system less active, it can help prevent transplant rejection from occurring.
 
(To learn more about this drug's mechanism of action, click Prograf Uses. This article covers a number of topics, such as whether Prograf is safe for use in children and possible off-label reasons a doctor may prescribe the drug.)
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