Prograf Drug Interactions

Silodosin
Prograf may increase the amount of silodosin in your blood, possibly increasing your risk for side effects. It is generally recommended that these medicines not be used together.
 
Sirolimus
People taking Prograf after a liver or heart transplant should not take sirolimus due to the increased risk for potentially serious side effects, such as kidney problems, diabetes, and slow wound healing. Sirolimus may also not be safe for people taking Prograf after a kidney transplant.
 
Topotecan
Prograf may increase the amount of topotecan in your blood, potentially increasing your risk for side effects. This interaction is expected to be more significant for oral topotecan, compared with the intravenous (IV) form. It is generally recommended that these medicines not be taken together.
 

Final Thoughts

Because Prograf can interfere with so many different medicines, it is not possible to discuss them all in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific interactions that may apply to you. Always double-check with your healthcare provider and your pharmacist before starting or stopping any medication while you are taking Prograf, due to the high risk for serious drug interactions.
 

Prograf Medication Information

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