Drug Interactions With Mycophenolate
The following sections explain in detail the potentially negative interactions that can occur when mycophenolate is combined with any of the drugs listed above.
Acyclovir and Valacyclovir
Combining mycophenolate with acyclovir or valacyclovir could increase your blood levels of both medications, potentially increasing your risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medicines together.
Antacids Containing Aluminum or Magnesium
Aluminum and magnesium can bind to mycophenolate in the digestive tract, decreasing the amount of the drug absorbed into your bloodstream. To reduce the risk of this interaction, do not take mycophenolate and antacids within two hours of each other.
Antibiotic medications may reduce the amount of mycophenolate in your blood, potentially making it less effective. Make sure your healthcare provider knows you are taking mycophenolate if you are given an antibiotic. Your mycophenolate blood levels should return to normal soon after you stop taking the antibiotic.
Azathioprine is an immunosuppressant medicine that works similar to mycophenolate. It is generally recommended that these two medications not be taken together.
Belatacept may increase blood levels of mycophenolate, potentially increasing the risk for side effects. Belatacept is approved for use in combination with mycophenolate to prevent kidney transplant rejection. If you are given this combination, your healthcare provider may choose to monitor you more closely when you first start taking these drugs together.