Kidneys Home > Votrient and Breastfeeding
No studies have been done to determine if Votrient (pazopanib) passes through human breast milk. However, because potentially serious side effects can occur with this medicine, the manufacturer recommends that women not take Votrient while breastfeeding. If your doctor recommends this medicine while nursing, closely monitor your child for possible side effects.
Can Breastfeeding Women Take Votrient?
Votrient® (pazopanib) is a prescription medication approved for the treatment of certain types of cancer, including advanced renal cell carcinoma (cancer that begins in the cells of the kidneys) and advanced soft tissue carcinoma (cancer that begins in the soft tissues, such as the muscles, nerves, and blood vessels) in adults. At this time, it is unknown whether Votrient passes through breast milk in humans. If you are currently breastfeeding a child, talk to your healthcare provider before taking this drug.
More Information About Votrient and Breastfeeding
Votrient has not been studied in women who were breastfeeding. Therefore, it is unknown if the medicine passes through breast milk or if it would harm a nursing infant. The manufacturer recommends women not use Votrient while breastfeeding. This is because many medicines pass through breast milk and because Votrient is associated with potentially serious side effects that could harm a nursing child.
Studies in young rats suggest that this medication could be quite dangerous in children, particularly young children. Giving Votrient to young rats (equivalent to under two years old in humans) resulted in toxicity to the lungs, heart, liver, and kidneys, as well as other problems, including death. Votrient is not approved for use in children. These risks should be considered when deciding if a woman should take Votrient while breastfeeding.
In general, this drug should probably not be taken while nursing until more information is available. However, if your healthcare provider recommends using Votrient while breastfeeding, watch for any possible side effects in your child and contact your child's healthcare provider if you notice anything that does not seem right.