Kidneys Home > Torisel Drug Interactions

To ensure a safe and effective treatment with Torisel, let your healthcare provider know about any other medications, vitamins, or supplements you are taking before beginning treatment. For example, negative interactions may occur if Torisel is combined with certain drugs, such as ACE inhibitors, cyclosporine, or live vaccinations. Some of these reactions may increase your risk for serious side effects or make the medications less effective.

An Overview of Interactions With Torisel

Torisel® (temsirolimus) may react with several other medications. Some of the drugs that may interact with Torisel include but are not limited to:
  • ACE inhibitors, such as:
  • CYP 3A4 inhibitor medications, such as:
  • Medications that "thin" the blood (such as anticoagulant and antiplatelet drugs), such as:


      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
  • P-glycoprotein inhibitors, such as:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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