Kidneys Home > Neoral Uses

People who have had a heart, liver, or kidney transplant may benefit from Neoral. Approved uses of this medicine also include the treatment of severe plaque psoriasis and severe rheumatoid arthritis in people who have not adequately responded to other treatments. In some cases, a healthcare provider may recommend "off-label," or unapproved, uses for Neoral, such as treating psoriatic arthritis, alopecia, and ulcerative colitis.

What Is Neoral Used For?

Neoral® (cyclosporine) is a prescription medication that belongs to a group of medicines called immunosuppressants. It is approved for the following uses:
  • Treating severe plaque psoriasis in certain people who are not adequately treated with, or cannot take, another treatment option
  • Treating severe, active rheumatoid arthritis in people who do not adequately respond to methotrexate (Rheumatrex®, Trexall®)
  • Preventing organ rejection after a kidney, liver, or heart transplant.

Neoral Use for Treating Psoriasis

Psoriasis is a chronic skin disease that causes areas of thickened, swollen, and red skin. It occurs when the immune system malfunctions, so that cells that normally protect the body against infection and disease are mistakenly put into action and trigger an immune response. This immune response leads to inflammation and a rapid turnover of skin cells.
There are several different types of psoriasis (see Types of Psoriasis). One type, plaque psoriasis, is characterized by skin lesions that are red at the base and covered by silvery scales. Neoral is approved for people with severe, extensive, or disabling plaque psoriasis, who otherwise have normal immune systems. It is only approved for use after at least one other treatment has failed, or in people who cannot take other medicines for their psoriasis.
Neoral helps improve symptoms of psoriasis, but it will not cure the condition. Psoriasis will likely return after Neoral treatment is stopped.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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