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Using Neoral for Transplant Rejection

The immune system works to defend the body against organisms, such as viruses, bacteria, parasites, and other potentially harmful substances. It does this by recognizing and destroying the foreign matter through a series of steps known as an immune response. Transplant rejection occurs when the immune system recognizes a newly transplanted organ as foreign matter and attacks it.
Anti-rejection medications, including Neoral, are given to suppress the immune system, and thus help prevent transplant rejection. Because anti-rejection medications suppress the immune system, they are also called immunosuppressants. These medicines are usually started just before surgery, or immediately afterwards.
Neoral is approved to prevent transplant rejection after a kidney, liver, or heart transplant. It is often used in combination with other medications, including azathioprine (Imuran®) and corticosteroids (such as prednisone).

How Does It Work?

Neoral works by making the immune system less active. An overactive immune system is involved in rheumatoid arthritis and psoriasis. Transplant rejection occurs when the body's immune system recognizes the transplanted organ as a foreign material and attacks it. By suppressing the immune system, Neoral can help prevent transplant rejection and ease symptoms of rheumatoid arthritis and psoriasis.

Is It Safe for Children to Take Neoral?

Neoral is approved for the prevention of transplant rejection in children as young as 1 year old. However, when used to treat psoriasis or rheumatoid arthritis, it is not approved for use in people younger than 18 years old. Talk to your child's healthcare provider about the risks and benefits of using Neoral in children.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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