Kidneys Home > Neoral Side Effects

Tremors, headaches, and excess facial hair growth are some of the most commonly reported side effects with Neoral. In most cases, reactions such as these are mild and generally easy to treat. However, notify your healthcare provider immediately if you develop potentially serious problems, such as seizures, chest pain, or difficulty breathing.

An Introduction to Neoral Side Effects

Just like any medicine, Neoral® (cyclosporine) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Neoral. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Neoral

Neoral has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Neoral or another cyclosporine medication (Sandimmune®) were carefully documented. The side effects observed in people taking Neoral were comparable to those observed in people taking Sandimmune.
In these clinical studies, the most commonly observed side effects included:
  • Tremors -- in up to 55 percent of people
  • Increased blood pressure (hypertension) -- up to 53 percent
  • Excess facial or body hair growth -- up to 45 percent
  • Kidney problems -- up to 38 percent
  • Headaches -- up to 25 percent
  • Infection of any kind -- up to 25 percent
  • Growth of extra gum tissue -- up to 16 percent
  • Abdominal (stomach) pain -- up to 15 percent
  • Pain -- up to 13 percent
  • Diarrhea -- up to 13 percent
  • Leg cramps -- up to 12 percent
  • Tingling, pricking, or numbing sensation of the skin -- up to 11 percent.
Other common side effects, occurring in 3 to 10 percent of people, included:
  • Swelling (edema) of the body
  • Nausea and vomiting
  • A rash
  • Heartburn or indigestion
  • Dizziness
  • Stuffy nose
  • Coughing
  • Shortness of breath
  • Sudden warmth and redness of the face and neck (flushing)
  • Acne
  • Chest pain
  • Breast enlargement
  • Joint or muscle pain
  • Fatigue
  • Gassiness
  • Hair loss (alopecia)
  • Insomnia
  • Flu-like symptoms
  • Migraine
  • Uncontrollable shaking
  • Cramps
  • Decreased appetite.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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