If you have a kidney transplant, your healthcare provider may prescribe Simulect® (basiliximab) to help prevent the rejection of your new kidney. This medicine works by binding to certain white blood cells to prevent them from attacking the newly transplanted kidney.
Simulect comes as a powder that is dissolved in fluid and given as an intravenous (IV) injection or infusion. It is administered by a healthcare provider in a healthcare setting. The first dose is given within two hours after transplant surgery, and the second dose is given four days later.
Before starting treatment with Simulect, make sure to review the medication's safety information with your healthcare provider. For example, you may not be able to use this medicine if you have certain allergies, cancer, or a history of transplant rejection.
Although most people tolerate Simulect well, side effects can occur. Some of the common reactions reported with this drug include nausea, headaches, and constipation.
(Click Simulect for more information on this medication, including detailed dosing guidelines, other safety warnings to be aware of, and what to do if you are pregnant or breastfeeding.)
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: ArthurSchoenstadt, MD
List of references (click here):
Simulect [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2005 September.
Food and Drug Administration Web site. Vaccines, Blood and Biologics, Resources for Healthcare Providers. Available at: http://www.fda.gov/BiologicsBloodVaccines/ResourcesforYou/HealthcareProviders/default.htm. Accessed September 30, 2011.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
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