As an immunosuppressant, Rapamune® (sirolimus) is approved to prevent organ rejection in people who have received a kidney transplant. It is used in combination with other medicines and is taken once a day. Rapamune is sold as a tablet and an oral solution (liquid).
In clinical studies, the most commonly reported side effects of this medication included:
Swelling (edema) of the hands, feet, ankles, and legs
It's important to review Rapamune's safety information with your healthcare provider before starting treatment. This medication may not be suitable for everyone, so make sure your healthcare provider is aware if you have any other medical conditions, such as high blood pressure, hepatitis, or skin cancer, or if you are taking any other types of medicine.
(Click Rapamune for more information on this medication, including how to use it, other safety issues to keep in mind during treatment, and how it works.)
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob. Accessed September 16, 2011.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed September 19 2011.
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