Orthoclone OKT®3 (muromonab-CD3) is a medication prescribed to treat organ rejection following a heart, kidney, or liver transplant. It comes as an intravenous (IV) injection that is administered by a healthcare provider for 10 to 14 days. Your specific dosage will depend on various factors, such as your age, weight, and how you respond to the drug.
While some people tolerate this medicine well, most people receiving it will develop some type of side effect. Some of the commonly reported reactions include diarrhea, nausea, and headaches.
Before starting treatment with Orthoclone OKT3, make sure to review the drug's safety information with your healthcare provider. For example, you may not be able to use this medicine if you have certain allergies, heart disease, or high blood pressure. Also, this product may react with certain other medications.
(For more information on this drug, click Orthoclone OKT3. This article offers a complete overview, including how it works, details on its safety and effectiveness, and more.)
Food and Drug Administration Web site. Vaccines, Blood and Biologics, Resources for Healthcare Providers. Available at: http://www.fda.gov/BiologicsBloodVaccines/ResourcesforYou/HealthcareProviders/default.htm. Accessed September 30, 2011.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2008.
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