Kidneys Home > Everolimus and Breastfeeding

Although it is unknown whether everolimus passes through human breast milk, it does pass through the breast milk of rats in high amounts. Due to the potentially serious complications this medicine may cause in a nursing child, the manufacturer of the drug recommends that women avoid taking everolimus while breastfeeding.

Can Breastfeeding Women Take Everolimus?

Everolimus (Afinitor®, Zortress®) is a prescription medication that belongs to a class of drugs called kinase inhibitors. It is used in certain types of cancer and tumors to help slow down the growth and spread of cancer and tumor cells, and after a kidney or liver transplant to help prevent the body from rejecting the new organ.
At this time, it is not known whether everolimus passes through breast milk in humans. The manufacturer of the medication recommends that women avoid breastfeeding while taking everolimus. Therefore, if you are nursing, talk with your healthcare provider prior to taking this medicine.

More Information on Everolimus and Breastfeeding

No research has been done to see if everolimus passes through breast milk in humans. In animal studies, the drug was shown to pass through the breast milk of rats in high amounts. The level of everolimus in the breast milk was higher than the level observed in the rats' bloodstream.
Everolimus is an immunosuppressant, which means it decreases the activity of the immune system. Because of the possibility that this drug may pass through human breast milk, and the potential for serious side effects in a nursing child, breastfeeding may not be advisable during treatment.

Talking With Your Healthcare Provider

You should discuss breastfeeding and everolimus use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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