Kidneys Home > CellCept Uses

A healthcare provider may prescribe CellCept following a kidney, heart, or liver transplant to help prevent the body from attacking and rejecting the new organ. This prescription medicine works by blocking certain enzymes in the body, making the immune system less active. There are also "off-label," or unapproved, uses for CellCept, such as treating kidney disease, atopic dermatitis, and lupus nephritis.

What Is CellCept Used For?

CellCept® (mycophenolate mofetil) is a prescription "anti-rejection" medication used in combination with other medicines to prevent organ rejection after a heart, kidney, or liver transplant. It belongs to a group of medicines called immunosuppressants.
An organ transplant is the transfer of a healthy organ from one person (an organ donor) into another person who has a failing organ (the organ recipient). Not all organs can be transplanted. Commonly transplanted organs include the kidneys, lungs, liver, heart, pancreas, and small intestine.
The immune system is responsible for protecting the body against potentially harmful foreign invaders. After an organ transplant, the immune system can tell that the new organ is not a normal part of the body. As a result, it may attack the new organ and try to get rid of it; this is called transplant rejection. Transplant rejection can cause the transplanted organ to fail.
Most people who receive an organ transplant need to take anti-rejection medicines, such as CellCept, for the rest of their lives to prevent transplant rejection from occurring. CellCept is used to prevent transplant rejection after a kidney, heart, or liver transplant. It is always used in combination with cyclosporine (Gengraf®, Neoral®, Sandimmune®) and a corticosteroid, or steroid medicine (such as prednisone).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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