What Is Everolimus Used For?

How Does Everolimus Work?

Protein kinases are enzymes found in the body that regulate cell function, including cell growth. Everolimus works by blocking the action of a specific protein kinase called the mammalian target of rapamycin (mTOR).
 
When mTOR is not functioning properly, as is the case in certain types of cancers and tumors, cells grow and multiply abnormally. mTOR also promotes blood vessel growth into tumors, which supplies cancer cells with nutrients and energy, and gives them a way to spread to other areas of the body.
 
By inhibiting mTOR, everolimus stops cancer and tumor cells from growing and multiplying. It also cuts off the blood supply to cancer cells, which may help slow down the spread of the cancer.
 
Everolimus works to prevent transplant rejection by weakening the immune system. When certain white blood cells, called lymphocytes, encounter a foreign material, they change into an active form and begin to reproduce rapidly so there are more of them available to fight the invading substance. Everolimus blocks the activation and rapid reproduction of the lymphocytes, thus preventing an immune response against the newly transplanted organ.
 

Can Children Use It?

Everolimus is approved for use in children with SEGA who are at least one year old. It has not been adequately studied in younger infants with SEGA, or individuals younger than 18 years old for other uses. The medication comes in special tablets (known as Disperz tablets) that can be mixed with water to make a suspension just before each dose for use in children with SEGA.
 

Can Older Adults Use It?

Everolimus may be used in older adults. In clinical trials, there were no notable differences in the safety or effectiveness of everolimus when comparing people younger than and older than age 65. However, some older adults may be more sensitive to the side effects of this medication, and therefore may need to be monitored more closely.
 
5 Easy Tips to Manage Visitors During Cancer Treatment

Everolimus Drug Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.