Precautions and Warnings With Everolimus

If you are undergoing treatment with everolimus, it is important to know that this medication may increase your risk for lung problems, serious infections, and angioedema. Also, this medication should not be taken by people who are taking certain medications or who have certain allergies. Other warnings and precautions with everolimus apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Taking Everolimus?

Talk with your healthcare provider prior to taking everolimus (Afinitor®, Zortress®) if you have:
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure (renal failure)
  • Had a heart transplant 
  • Diabetes
  • High cholesterol or high triglycerides
  • Skin cancer or a family member who has had skin cancer
  • An infection of any kind
  • A history of hepatitis B
  • Genetic problems digesting the sugar galactose, such as glucose-galactose malabsorption or Lapp lactase deficiency
  • Plans to receive a vaccine or will be in close contact with someone who will be receiving a vaccine
  • A blood clotting disorder
  • Anemia or other blood cell problems
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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Everolimus Drug Information

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