Everolimus Dosage

Before prescribing a specific everolimus dosage, your healthcare provider will take into consideration other existing medical conditions you may have and other medications you are taking, among various other factors. This medication comes in the form of a tablet and a dispersible tablet, and is typically taken once or twice a day. Your specific amount may be adjusted based on your blood levels of everolimus.

An Introduction to Your Everolimus Dosage

The dose of everolimus (Afinitor®, Zortress®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The reason you are using the medicine
  • How you respond to it
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Everolimus Dosing for Pancreatic and Kidney Cancer

The recommended everolimus dose for the treatment of advanced renal cell carcinoma (kidney cancer) and advanced pancreatic neuroendocrine tumor (PNET) is typically everolimus 10 mg once daily.
The recommended dosage for people with mild liver disease is 7.5 mg a day. The dose may be reduced to 5 mg a day if the higher dose is not tolerated. The recommended dosage for people with moderate liver disease is 5 mg daily. The dose may be reduced to 2.5 mg a day if 5 mg is not tolerated. People with severe liver disease should be given no more than 2.5 mg of everolimus daily.
People who experience intolerable or serious side effects may need to stop taking the medicine, or take a lower dosage, at least temporarily. Also, higher or lower doses may be used in people taking certain medications that are known to negatively react with everolimus (see Drug Interactions With Everolimus).
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Everolimus Drug Information

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