Drug Interactions With Azasan
More Information on Drug Interactions With AzasanThe following sections explain in detail the potentially negative reactions that can occur when Azasan is combined with any of the drugs listed above.
Allopurinol inhibits one of the enzymes that helps to remove Azasan from the body. If you take these medications together, your healthcare provider should reduce your Azasan dosage to about one-third to one-fourth of the usual dose.
Aminosalicylates can increase the level of Azasan in your blood, potentially increasing the risk for Azasan side effects. Your healthcare provider may need to decrease your Azasan dosage to prevent this interaction from occurring.
Angiotensin-Converting Enzyme Inhibitors
Combining an ACE inhibitor with Azasan can increase your risk for anemia or leukopenia (low levels of certain white blood cells called leukocytes). Talk to your healthcare provider before taking these medications together.
There have been reports of a highly aggressive and fatal form of cancer known as hepatosplenic T-cell lymphoma in people who took infliximab with Azasan, especially in young males being treated for Crohn's disease or ulcerative colitis. You and your healthcare provider should carefully discuss this risk before combining these two medications.
Sulfamethoxazole and Trimethoprim
Taking Azasan with sulfamethoxazole and trimethoprim can increase your risk of leukopenia. Talk to your healthcare provider before taking these medications together.
Azasan may decrease the effectiveness of warfarin, possibly increasing your risk for blood clots. Your healthcare provider should monitor you closely and adjust your warfarin dosage as necessary.